Nature Communications

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Use of ratiometrically designed nanocarrier targeting CDK4/6 and autophagy pathways for effective pancreatic cancer treatment
Ji Y. Liu X.S. Li J. Xie X.D. Huang M. Jiang J.H. Liao Y.P. Donahua T. Meng H.*
DOI: 10.1038/s41467-020-17996-7
This study presents a novel nanoformulation for pancreatic cancer, co-delivering CDK4/6 and autophagy inhibitors. Methodology demonstrates enhanced intratumoral drug accumulation, yielding superior tumor shrinkage and synergistic efficacy, suggesting significant potential for improved cancer therapies. Read more